Merkel-cell carcinoma in Behçet's disease.

Sir, Merkel-cell carcinoma (MCC) is a rare malignant tumour of the skin which is highly aggressive; frequent recurrences and distant spread are common (1). Behçet’s disease (BD) is a multisystem vasculitis, with oral and genital aphthous ulcers, cutaneous vasculitis, uveitis and arthritis as its main features (2). Association of BD with malignant tumours, mainly solid neoplasms, has been described, but a review of the literature showed no report of an association between BD and cutaneous tumours. We herein report the case of a patient affected with BD who subsequently developed a MCC.